After a live action sequence in which Walt Disney himself gives a tour of his animation studios in California, the action shifts to South America where a collection of both stock and new characters appear in a series of shorts. In one segment, Donald Duck (Clarence Nash) attempts to navigate Lake Titicaca with an uncooperative llama, and in another, a brave little airplane crosses the dangerous Andes. Meanwhile, Goofy (Pinto Colvig) tries to act like a local in the Pampas.
